MCB241W : Fall, 2005

Dr. David R. Benson

Rm 408 BSP

david.benson@uconn.edu

Prospectus

List of Articles: A new article will be discussed in each session. Critiques are completed in three stages: first draft, peer reviewed draft and final copy. The due dates are given below.

Date	Draft Due	To Peer Rev.	Final Copy Due	Title
Aug30	-	-	-	Introduction and organizational
Sept 1	#1 due			#1 C. A. Kerfeld et al., 2005. Protein Structures Forming the Shell of Primitive Bacterial Organelles. Science 309:936-938.
6				In situ stable isotope probing of methanogenic archaea in the rice rhizosphere. Science 309:188-191.
8	#2 due	#1		#2 Export-mediated assembly of mycobacterial glycoproteins parallels eukaryotic pathways. Science 309:941-943.
13				Containing pandemic influenza at the source. Science 309:1083-1085
15	#3 due	#2	#1	#3 The hangover gene defines a stress pathway required for ethanol tolerance development. Nature 436:845-848.
20				A Fluoroquinolone Resistance Protein from Mycobacterium tuberculosis That Mimics DNA Hegde,S. et al. Science 308:1480-1483.
22	#4 due	#3	#2	#4 Marketon, M. M. et al. 2005. Plague bacteria target immune cells during infection. Science 309:1739-1741.
27				Makinoshima, H. & M. Glickman. 2005. Regulation of Mycobacterium tuberculosis cell envelope composition and virulence by intramembrane proteolysis. Nature 436:406-409.
29	#5 due	#4	#3	#5 Bais, H. P. et al., 2005. Mediation of pathogen resistance by exudation of antimicrobials from roots. Nature 434:217-221.
Oct 4				Nandhini Ramamoorthi, et al., 2005. The Lyme disease agent exploits a tick protein to infect the mammalian host. Nature 436:573
6	#6 due	#5	#4	#6 Eckburg, P. B. et al., Diversity of the human instestinal microbial flora. Science. 308:1635
11				Blandford, S. et al, 2005. Fungal pathogen reduces potential for malaria transmission. Science 308:1638
13	#7	#6	#5	#7aShort review of Gibberellin #7bUeguchi-Tanaka, M. et al., 2005. Gibberellin insensitive Dwarf1 encodes a soluble receptor for gibberellin. Nature 437:693
18				Frank Zappulla/Martin Wojtyniak Alono, S. et al. 2005. The place of the Basques in the European Y-chromosome diversity landscape. Eur. J. Human Gen. 1-10
20	#8	#7	#6	#8 Mygind, P. H. et al. 2005. Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus. Nature 1038:975.
25				Jakub Bartnik - Scott, M. R. et al., 2005. Transmission barriers for bovine, ovine, and human prions in transgenic mice. J. Virol. 79:5259-5271.
27	#9	#8	#7	Jakub Latusek & Jelal Alsubai - Chandran, K. et al., 2005. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science 308:1643.
Nov 1				No Class
3				David Brenneman/G. Rdzak - HST2 mediates SIR2-independent life-span extension by calorie restriction. Science. 309:1861.
8				Artan Ismaili/Ivan Gueorguiev - Boyden, E. S., et al. 2005. Millisecond-timescale, genetically targeted optical control of neural activity. Nature Neuroscience Advanced on-line pub. 8/14/05
10				Joseph Kononchik - Hung, D. T. et al., 2005. Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization. Science 310:670
15				Denise Grant - Kujoth, G. C. et al., 2005. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309:481.
17				Ibrahim Shihadeh/Mike Sortito - Dashper, S. G. et al., 2005. Divalent metal cations increase the activity of the antimicrobial peptide kappacin. Antimicrobial. Ag. Chemother. 49:2333-2328.
22				Thanksgiving Break
24				Thanksgiving Break
29				Raja Das - Fineschi, V. et al. 2005. Sudden cardiac death during anabolic steroid abuse: morphologic and toxicologic findings in two fatal cases of bodybuilders. Int. J. Legal Med. On-Line
Dec 1				Daveneet Rahndhawa/Zuhair Qureshi - Johnston, K. L., et al. 2005. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J. Clin. Nutr. 78:728-33.
6				Emily Kolk - Holland, P. R. et al. 2005. Oxexin 1 receptor activation attenuates neurogenic dural vasodilation in an animal model of trigeminovascular nociception. J. Pharm. Exp. Therapeutics 315:1380
8				Anna Mironets/Manjot Kaur - Klueh, U. & D. L. Kreutzer. 2005. Murine model of implantable glucose sensors: a novel model for glucose sensor development. Diabetes Technol & Therap.