Both semesters. Four credits. Two 2-hour lectures. Prerequisite: MCB 203; MCB 200 or 213; all of which may be concurrent. Open to students in the Diagnostic Genetic Sciences Program; others who have met the prerequisites.

Birth defects, prenatal assessment, cell culture and harvest, staining and banding techniques, mechanisms of numerical and structural chromosome abnormality, numerical syndromes, duplication and deletion syndromes, the sex chromosomes, sex chromosome abnormalities, human chromosome nomenclature, mosaicism, genetic imprinting, cancer cytogenetics, molecular cytogenetic testing.

Both semesters. Three credits. One 3-hour laboratory period and 1-hour discussion. Four additional laboratory sessions are required during the first half of the semester. Prerequisite: DGS 222 which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with consent of instructor.

Human chromosome morphology and identification, aseptic technique, lymphocyte culture and harvest, chromosome banding, karotyping and microscopic analysis of normal and abnormal cases.

Offered Summer I.  Variable credits.  Prerequisite: DGS 222.  Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with consent of instructor.

Chromosome instability syndromes, genetic basis of cancer, cytogenetics of solid tumors and hematologic malignancies, and nomenclature of acquired changes.

Both semesters. Three credits. Prerequisite: MCB 200 or 213; and MLS 208 or MCB 211 which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with instructor consent.

DNA and RNA diagnostic technologies used in clinical settings; clinical applications in prenatal diagnosis; cancer management, transplantation, paternity testing, forensic medicine and microbiology.

Both semesters. Four credits. Prerequisite: DGS 234 or MLS 217 which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetic Sciences Program; others by consent of instructor.

DNA isolation, blotting techniques, fluorescent in situ hybridization, polymerase chain reaction and Genprobe assay.

First semester and Summer Session I. Two credits. Two hours of lecture and 1 hour of discussion. Prerequisites: DGS 222 and 223. Open only to DGS majors; others with consent of instructor. Fall offering open only to DGS students with a Spring Clinical.

Theory and techniques of bright field microscopy, black and white film processing and printing, and computerized imaging for karyotype production.

Both semesters. Three credits. Prerequisite: DGS 223  and DGS 222.  Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with consent of the instructor.

Advanced karotyping and microscopic diagnosis; report writing; historical perspective; recent advances and future trends in human genetics; ethical issues of genetic research, technological advances, genetic diagnosis and the practice of medical genetics; exploration of the lay person's understanding of human genetics and genetic diagnosis.

Both semesters. Six credits. Prerequisite: DGS 234 and 235. Open only to DGS molecular certificate students.

Practicum experience with blotting technologies stressing complete Southern analysis.

Both semesters. Six credits. Prerequisite: DGS 234 and 235. Open only to DGS molecular certificate students.

Practicum experience in DNA and/or RNA amplification stressing polymerase chain reaction.

Both semesters. One credit. Prerequisites: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.

Design and implementation of a research project in molecular genetics.

Both semesters. Two credits. Prerequisites: DGS 234 and 235. Open only to DGS molecular certificate students.

Practicum in fluorescence in situ hybridization or other in situ hybridization techniques.

Both semesters. Two credits. Prerequisite: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.

Exploration of an individual area of interest in molecular genetics.

Both semesters. Two credits. Prerequisite: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.

Practicum experience in mutagenesis, including Ames assays and mammalian mutagenesis assays.

Both semesters. Two credits. Prerequisite: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.

Practicum experience in DNA sequencing.

Both semesters. Two credits. Prerequisite: DGS 234 and DGS 235. Open only to students enrolled in the Molecular Diagnostic Sciences Certificate Program; others with consent of the instructor.

Practicum experience in the application of molecular technologies to microbiology.

Both semesters. Two credits. Prerequisite: In order to enroll in the course, the student must have earned a "C" or better in DGS 222 and DGS 223. Open only to Diagnostic Genetic Sciences majors. 

Culture, harvest, banding and analysis of leukemic bone marrow samples; chromosomal abnormalities associated with hematologic malignancies.

Both semesters. Four credits. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 and DGS 223. Open only to Diagnostic Genetic Sciences majors. 

Culture, harvest, banding and analysis of peripheral blood samples.

Both semesters. One credit. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 and DGS 223. Open only to Diagnostic Genetic Sciences majors. 

Utilization and application of special staining and banding techniques, karotyping of normal and abnormal metaphases from all specimen types.

Both semesters. One credit. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 , DGS 223, and DGS 242. Open only to Diagnostic Genetic Sciences majors. 

Techniques of photomicroscopy, B/W film development, print enlargement, computer imaging.

Both semesters. One credit. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 and DGS 223. Open only to Diagnostic Genetic Sciences majors. 

In-depth examination of a topic of the students' choosing in the field of human genetics.

Both semesters. One credit. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222  and DGS 223. Open only to Diagnostic Genetic Sciences majors. 

Design and implementation of a research project in clinical cytogenetics.

Both semesters. Four credits. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 222 and DGS 223. Open only to Diagnostic Genetic Sciences majors. 

Culture, harvest, banding and analysis of amniotic fluids, products of conception, and other fetal samples.

Either semester. Credits and hours by arrangement. Prerequisite: The completion of all Lower Division requirements in the Diagnostic Genetic Sciences Program. Open only with consent of instructor. May be repeated for credit.

Application of the scientific method of inquiry to planning, implementation, evaluating and reporting a study of a problem in cytogenetics.

Either semester. Credits and hours by arrangement. Open only with consent of instructor. May be repeated for credit.

This course is designed primarily for students who wish to extend their knowledge in some specialized area in the field of diagnostic genetic sciences.